Antihistamine is one of the pharmacological class out of the many among it
Antihistamine is one of the pharmacological class out of the many among it. It is widely used to treat allergies and flu symptoms. It can be used as Histamine-1 receptor to block histamine from releasing. The receptors are usually found at the airway, blood vessels and gastrointestinal tract (GI), spinal cord and in the brain.
Antihistamines can be used for swelling, teary eyes and itch or rashes. Those people who suffer from allergies can prevent the irritation by taking antihistamine related drugs. It is not always successful as allergic reactions are usually caught by breathing in air making it harder to avoid. It takes a short time to treat antihistamines. It has two receptors that Antihistamine targets the both receptors called Histamine H1 receptor and Histamine H2 receptor. Antihistamine has different targets for Histamine H1 receptors such as treating allergic reactions and insomnia but Histamine H2 receptors used to target gastric acid conditions. Antihistamine has two generations. It comes in the form of tablet, syrup and oral drops. The first Antihistamine generations drug are usually drowsy, and it can be quite lethal for infants or young children. The second Antihistamine generation is usually less drowsy and does not cause fatality in overdose. The specific H1 receptor is used as a standard treatment against allergic rhinitis. The first-generation Antihistamines contains small lipophilic molecules that may lead to adverse events causing cholinergic activity and to cross to the blood-brain barrier. Whereas the second-generation Antihistamines contains more lipophilic which offers effects like sedation or dry mouth that would be commonly seen in first-generation Antihistamines. Its longer duration of drug action helps the dosing regimen to increase in the patient’s body.